|
|
ATP + (R)-pantoate <=> H+ + ADP + (R)-4-phosphopantoate
|
2.7.1.169
pantoate kinase
|
–
|
|
BRENDA:
BR49258;
BS407155
KEGG:
R09378
MetaCyc:
RXN-11782
|
|
|
|
(R)-pantoate + beta-Alanine + ATP <=> pantothenate + ADP + phosphate + H+
|
6.3.2.44
pantoate---beta-alanine ligase (ADP-forming)
|
–
|
|
BRENDA:
BR50564
KEGG:
R10821
MetaCyc:
RXN-14175
|
|
|
|
beta-Alanine + (R)-pantoate + ATP <=> H+ + pantothenate + diphosphate + AMP
|
6.3.2.1
pantoate---beta-alanine ligase (AMP-forming)
|
–
|
|
BRENDA:
BR101
KEGG:
R02473
MetaCyc:
PANTOATE-BETA-ALANINE-LIG-RXN
SABIO-RK:
2406
|
|
|
|
(R)-pantoate + NADP+ <=> H+ + ketopantoate + NADPH
|
1.1.1.169
2-dehydropantoate 2-reductase
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
–
|
|
BRENDA:
BR29231;
BS187414;
BS434963
KEGG:
R02472
MetaCyc:
2-DEHYDROPANTOATE-REDUCT-RXN
SABIO-RK:
2405
|
|
|
|
(R)-4-phosphopantoate + beta-Alanine + ATP <=> (R)-4''-phosphopantothenate + AMP + diphosphate + H+
|
6.3.2.36
4-phosphopantoate---beta-alanine ligase
|
–
|
|
BRENDA:
BR49268;
BS407112
KEGG:
R09379
MetaCyc:
RXN-11781
|
|
|
|
5,10-methylenetetrahydrofolate + 2-oxoisovalerate + H2O <=> ketopantoate + tetrahydrofolate
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
BRENDA:
BR43940
KEGG:
R01226
MetaCyc:
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN
SABIO-RK:
1455
|
|